Solid dosing in High-Throughput Experimentation: generalization of mass enhancer technologies for submilligram scale - CEA - Commissariat à l’énergie atomique et aux énergies alternatives
Article Dans Une Revue Journal of flow chemistry Année : 2024

Solid dosing in High-Throughput Experimentation: generalization of mass enhancer technologies for submilligram scale

Résumé

The emergence of High-Throughput Experimentation (HTE) as a powerful tool for reaction discovery and optimization is changing the way organic chemists are designing their experiments. It is a fantastic way to largely investigate a reaction, in a minimum of time and reagent consumption. However, HTE needs to be accessible to a wide audience for a full implementation in academic and industrial sectors. In that context, developing accessible solid dosing methodologies for submilligram dispensing is necessary. This paper aims at proposing robust mass enhancers solutions for nanomole scale dosing applicable to HTE campaigns.

Domaines

Chimie
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Dates et versions

cea-04448659 , version 1 (09-02-2024)

Identifiants

Citer

Taline Kerackian, Géraud Chacktas, Didier Durand, Eugénie Romero. Solid dosing in High-Throughput Experimentation: generalization of mass enhancer technologies for submilligram scale. Journal of flow chemistry, 2024, 14 (1), pp.367-375. ⟨10.1007/s41981-023-00304-x⟩. ⟨cea-04448659⟩
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