The triple to double coincidence ratio (TDCR) liquid scintillation measurement technique is commonly used in national metrology institutes (NMIs) to perform standardization of pure beta emitters. The LNE-LNHB historical device, RCTD1, is a quite large device, which has been developed and commonly used over the past 30 years with its associated electronics for measurements of various radionuclides. During the last 4 years LNE-LNHB has developed two new portable TDCR devices. Such portable instrumentation gives end-users access to a reference measurement method that can be used for a large number of radionuclides. It addresses a wide range of industrial and medical applications for radionuclide metrology, including calibrations of solutions containing short-lived radionuclides, avoidance of radioactive source transportation, and performing on-site comparison to promote radionuclide metrology harmonization. In this paper, we will present the newly developed portable TDCR liquid scintillation measurement systems. Two kinds of devices have been developed and designed at LNE-LNHB and built using fused deposition modelling (FDM) 3D printing: a mini-TDCR (25 cm diameter, 10 cm height) and a micro-TDCR (16 cm diameter, 10 cm height). After a detailed discussion of the design and the possibilities offered by 3D printing for their conception, this paper will present the performance of the devices obtained for several radionuclides. The results will be compared with the RCTD1 in order to validate the performance of the new devices. They exhibit improved performance, such as higher detection efficiency, and include various useful tools for proper on-site metrology. The first tests, which were performed in Orsay Hospital (CEA/SHFJ) and in another laboratory (IRSN), allowed us to show the very good overall performance of the systems including their outstanding linearity, which was tested in the range from 430 000 s$^{−1}$ down to 160 s$^{−1}$ in the double coincidences channel. Applications of the developed systems for high and low activity measurements are also discussed. Finally, the portable device has been used for half-life measurements in order to check for impurities in a radio-pharmaceutical solution.