$^{68}$GA activity calibrations for nuclear medicine applications in Cuba - CEA - Commissariat à l’énergie atomique et aux énergies alternatives Access content directly
Journal Articles Applied Radiation and Isotopes Year : 2018

$^{68}$GA activity calibrations for nuclear medicine applications in Cuba

Abstract

The realization and dissemination of the $^{68}$Ga activity measurement unit in Cuba is presented. Firstly, the implementation of the Triple to Double Coincidence Ratio (TDCR) method is described for the calibration of the activity concentration of a $^{68}$Ga solution using a Hidex (TM) commercial liquid scintillation counter and a FORTRAN code developed for the calculation of the $^{68}$Ga counting efficiencies in the given measurement system. The relative expanded uncertainty ($k$ = 2) associated with the $^{68}$Ga activity concentration obtained with the TDCR method is equal to 2%. With the aim to validate this measurement uncertainty estimate, the method is also applied to an Amersham standard solution of $^{22}$Na - a positron emitter with a similar decay mode to the $^{68}$Ga disintegration scheme from the point of view of type of emitted particles detected in the measurement system. The observed difference between the measured $^{22}$Na activity concentration by the TDCR method and the corresponding reference value traceable to NIST is equal to 0.16%. Outcomes of transferring the $^{68}$Ga activity standard, realized with the TDCR method, to the secondary standard radionuclide calibrator Capintec CRC™ 15R and to three radionuclide calibrators used for $^{68}$Ga PET applications in a hospital are also shown.
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Dates and versions

cea-01803822 , version 1 (27-06-2023)

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P. Oropesa Verdecia, L. Garcia Rodriguez, R. A. Serra Aguila, Y. Moreno Leon, Y. Jenez Magana, et al.. $^{68}$GA activity calibrations for nuclear medicine applications in Cuba. Applied Radiation and Isotopes, 2018, ICRM 2017 Proceedings of the 21st International Conference on Radionuclide Metrology and its Applications, 134 (SI), pp.112-116. ⟨10.1016/j.apradiso.2017.11.010⟩. ⟨cea-01803822⟩
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