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Conference Poster Year : 2021

Biophysical study of large macromolecular complexes


Large macromolecular complexes are ubiquitous in biological media (e.g. protein complexes, membrane-bound complexes…). Specific biophysical techniques can be used to assess the interactions and structures of such complexes. Two independent systems were chosen as examples. The first one deals with the formation of protein coronas (protein/nanoparticle interactions) while the second system concerns virus encapsidation (protein/RNA interactions). Here, we can see how three techniques (isothermal titration calorimetry, cryoelectron microscopy, and small angle scattering) can be combined in order to answer fundamental questions.
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cea-03356115 , version 1 (27-09-2021)


  • HAL Id : cea-03356115 , version 1


Laurent Marichal, Jean Philippe Renault, Jeril Degrouard, Rafael Leite Rubim, Guillaume Tresset, et al.. Biophysical study of large macromolecular complexes. Physbio2021 - 5th International Conference on Physics & Biological Systems, Jun 2021, E-Conference, France. . ⟨cea-03356115⟩
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