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Laser cooling of solids: towards biomedical applications


Focal cooling is a promising alternative therapy for intractable focal epilepsies, avoiding the irreversible neuronal damages induced by resection surgery. However, due to thermal conduction losses, local cooling of a deep brain region remains a challenging objective for thermoelectric or fluidic technologies. Here, we investigated the viability of an optical micro-cooler based on anti-Stokes refrigeration of ytterbium doped YLF crystals, taking into account the medical constraints for implantable device. We realized significant cooling under atmospheric pressure and developed a solution drastically reducing the harmful fluorescence heating of brain-like liquids below 2 K, thus demonstrating the relevance of this technology for biomedical applications.
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cea-02098375 , version 1 (12-04-2019)



Quentin Mermillod, Johan Cazals, Mathieu Dupoy, Alain Glière, Nicolas Aubert, et al.. Laser cooling of solids: towards biomedical applications. Photonic Heat Engines: Science and Applications, Feb 2019, San Francisco, United States. pp.21, ⟨10.1117/12.2507828⟩. ⟨cea-02098375⟩
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