New technologies for DNA analysis – a review of the READNA Project
Steven Mcginn
(1)
,
David Bauer
(2)
,
Thomas Brefort
(3)
,
Liqin Dong
(2)
,
Afaf El-Sagheer
(4, 5, 6)
,
Abdou Elsharawy
(7, 4)
,
Geraint Evans
(8)
,
Elin Falk-Sörqvist
(9)
,
Michael Forster
(7)
,
Simon Fredriksson
(10)
,
Peter Freeman
(11)
,
Camilla Freitag
(12)
,
Joachim Fritzsche
(13)
,
Spencer Gibson
(11)
,
Mats Gullberg
(10)
,
Marta Gut
(14)
,
Simon Heath
(14)
,
Isabelle Heath-Brun
(14)
,
Andrew Heron
(5)
,
Johannes Hohlbein
(15)
,
Rongqin Ke
(16)
,
Owen Lancaster
(11)
,
Ludovic Le Reste
(15)
,
Giovanni Maglia
(17)
,
Rodolphe Marie
(18)
,
Florence Mauger
(1)
,
Florian Mertes
(19)
,
Marco Mignardi
(16)
,
Lotte Moens
(16)
,
Jelle Oostmeijer
(20)
,
Ruud Out
(20)
,
Jonas Nyvold Pedersen
(18)
,
Fredrik Persson
(12)
,
Vincent Picaud
(21)
,
Dvir Rotem
(22)
,
Nadine Schracke
(23)
,
Jennifer Sengenes
(1)
,
Peer Stähler
(23)
,
Björn Stade
(7)
,
David Stoddart
(22)
,
Xia Teng
(20)
,
Colin Veal
(11)
,
Nathalie Zahra
(11)
,
Hagan Bayley
(22)
,
Markus Beier
(23)
,
Tom Brown
(24)
,
Cees Dekker
(25)
,
Björn Ekström
(10)
,
Henrik Flyvbjerg
(18)
,
Andre Franke
(7)
,
Simone Guenther
(26)
,
Achillefs Kapanidis
(15)
,
Jane Kaye
(27)
,
Anders Kristensen
(18)
,
Hans Lehrach
(19)
,
Jonathan Mangion
(26)
,
Sascha Sauer
(19)
,
Emile Schyns
(28)
,
Jörg Tost
(1)
,
Joop M.L.M. van Helvoort
(20)
,
Pieter J. van der Zaag
(29)
,
Jonas Tegenfeldt
(30)
,
Anthony Brookes
(11)
,
Kalim Mir
(2)
,
Mats Nilsson
(31)
,
James Willcocks
(30)
,
Ivo Gut
(14)
1
CNG -
Centre National de Génotypage
2 The Wellcome Trust Centre for Human Genetics [Oxford]
3 Guided Development Heidelberg GmbH [Heidelberg, Germany]
4 Damietta University
5 University of Oxford
6 Suez University
7 CAU - Christian-Albrechts-Universität zu Kiel = Christian-Albrechts University of Kiel = Université Christian-Albrechts de Kiel
8 University of Oxford, Clarendon Laboratory, Parks Road
9 GU - Göteborgs Universitet = University of Gothenburg
10 Olink AB - Olink AB, Dag Hammarskjölds väg 52A, 752 37 Uppsala, Sweden
11 University of Leicester
12 Department of Physics [Gothenburg]
13 Chalmers University of Technology [Göteborg]
14 CNAG - Centro Nacional de Analisis Genomico [Barcelona]
15 Clarendon Laboratory [Oxford]
16 Science for Life Laboratory [Solna]
17 Department of Chemistry [Oxford]
18 DTU Nanotech
19 MPIMG - Max Planck Institute for Molecular Genetics
20 FlexGen BV - FlexGen BV, Galileiweg 8, 2333 BD Leiden, The Netherlands
21 LS2D (CEA, LIST) - Laboratoire Sciences des Données et de la Décision (CEA, LIST)
22 Department of Chemistry, University of Oxford
23 Technologiepark Heidelberg GmbH
24 School of Chemistry [Southampton, UK]
25 KI-NANO - Kavli Institute of Nanosciences [Delft]
26 Thermo Fisher Scientific Inc.
27 HeLEX - Centre for Health, Law and Emerging Technologies
28 PHOTONIS FRANCE - Photonis France
29 Philips Research Laboratories [Eindhoven]
30 Oxford Nanopore Technologies
31 IGP - Department of Immunology, Genetics and Pathology [Uppsala, Sueden]
2 The Wellcome Trust Centre for Human Genetics [Oxford]
3 Guided Development Heidelberg GmbH [Heidelberg, Germany]
4 Damietta University
5 University of Oxford
6 Suez University
7 CAU - Christian-Albrechts-Universität zu Kiel = Christian-Albrechts University of Kiel = Université Christian-Albrechts de Kiel
8 University of Oxford, Clarendon Laboratory, Parks Road
9 GU - Göteborgs Universitet = University of Gothenburg
10 Olink AB - Olink AB, Dag Hammarskjölds väg 52A, 752 37 Uppsala, Sweden
11 University of Leicester
12 Department of Physics [Gothenburg]
13 Chalmers University of Technology [Göteborg]
14 CNAG - Centro Nacional de Analisis Genomico [Barcelona]
15 Clarendon Laboratory [Oxford]
16 Science for Life Laboratory [Solna]
17 Department of Chemistry [Oxford]
18 DTU Nanotech
19 MPIMG - Max Planck Institute for Molecular Genetics
20 FlexGen BV - FlexGen BV, Galileiweg 8, 2333 BD Leiden, The Netherlands
21 LS2D (CEA, LIST) - Laboratoire Sciences des Données et de la Décision (CEA, LIST)
22 Department of Chemistry, University of Oxford
23 Technologiepark Heidelberg GmbH
24 School of Chemistry [Southampton, UK]
25 KI-NANO - Kavli Institute of Nanosciences [Delft]
26 Thermo Fisher Scientific Inc.
27 HeLEX - Centre for Health, Law and Emerging Technologies
28 PHOTONIS FRANCE - Photonis France
29 Philips Research Laboratories [Eindhoven]
30 Oxford Nanopore Technologies
31 IGP - Department of Immunology, Genetics and Pathology [Uppsala, Sueden]
Steven Mcginn
- Fonction : Auteur
- PersonId : 1229005
- ORCID : 0000-0001-9418-6333
Spencer Gibson
- Fonction : Auteur
- PersonId : 1229006
- ORCID : 0000-0003-0768-1542
Florence Mauger
- Fonction : Auteur
- PersonId : 1383173
- IdHAL : florence-mauger
- ORCID : 0000-0002-8402-4338
Jelle Oostmeijer
- Fonction : Auteur
- PersonId : 1229007
- ORCID : 0000-0002-9121-1553
Jennifer Sengenes
- Fonction : Auteur
- PersonId : 1229008
- ORCID : 0000-0001-6865-4738
Jörg Tost
- Fonction : Auteur
- PersonId : 764992
- ORCID : 0000-0002-2683-0817
- IdRef : 123772389
Ivo Gut
- Fonction : Auteur
- PersonId : 1183785
- ORCID : 0000-0001-7219-632X
Résumé
The REvolutionary Approaches and Devices for Nucleic Acid analysis (READNA) project received 12 million s funding under the European Union Framework Programme 7 from 1st June 2008 to 30th November 2012. The 19 project partners from both academia and industry from in total 7 countries had a project budget of 16 Ms with which they have discovered, created and developed a huge body of insights into nucleic acid analysis. Results have been presented widely in publications and in innumerous public presentations. Results have been moved to spin-offs such as the Olink enrichment kits (now sold by Agilent as Haloplex) and are finding
their way to the market, such as the Oxford Nanopore MinIon sequencer that was first released to early-access user sites in 2014.
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