This paper presents the assessment of CATHARE 3 code against tests performed in the horizontal TPTF (Two Phase Tests Facility) and Mantilla facilities. This activity falls within the framework of a benchmark conducted by the Forum & Network of System Thermal-Hydraulics Codes in Nuclear Reactor Thermal-Hydraulics (FONESYS). The aim of this benchmark is to highlight the capabilities of system thermal–hydraulic codes to predict the horizontal stratification criteria and the onset of droplet entrainment and entrainment rate. One of the objectives of horizontal TPTF (TPTF-H) experiments, conducted by JAERI (Japan), was to analyse the thermal–hydraulic responses in the horizontal legs of Light Water Reactors. The considered tests were at steady state and saturated steam/water two-phase flow conditions for a pressure varying between 3 MPa and 12 MPa. CATHARE code simulations show a general rather good agreement with TPTF-H experimental results although some improvements like the stratification regime prediction seem necessary. In two horizontal test sections with different diameters, Mantilla carried out air/water experiments at low pressure, from stratified to annular flow conditions, including droplet entrainment. Entrainment fraction obtained both with the two-fluid 6-equation model and the 3-field model of CATHARE are compared against the experimental data. Some improvements of the existing models are proposed for the entrainment and deposition processes to better fit the experiments.