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authIdHal_s : denis-servent
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Editorial : Special issue on "toxins: from threats to benefits".

Marie-France Martin-Eauclaire , Evelyne Benoit , P. Marchot , Julien Barbier , Jordi Molgó , et al.
Toxicon, 2013, 75, pp.1-2. ⟨10.1016/j.toxicon.2013.08.001⟩
Journal articles hal-00919888v1

The three-finger toxin fold: a multifunctional structural scaffold able to modulate cholinergic functions

Pascal Kessler , P. Marchot , Marcela Silva , Denis Servent
Journal of Neurochemistry, 2017, 142, pp.7 - 18. ⟨10.1111/jnc.13975⟩
Journal articles hal-01802811v1

Synthesis and biology of cyclic imine toxins, an emerging class of potent, globally distributed marine toxins.

Craig E Stivala , Evelyne Benoit , Rómulo Aráoz , Denis Servent , Alexei Novikov , et al.
Natural Product Reports, 2015, 32 (3), pp.411-35. ⟨10.1039/c4np00089g⟩
Journal articles hal-01178830v1

Diversity in the binding interactions of marine phycotoxins to AChBP, the soluble nAChR surrogate

P. Marchot , Gerlind Sulzenbacher , Zoran Radic , Rómulo Aráoz , Emmanuelle Reynaud , et al.
XVth International Symposium on Cholinergic Mechanisms, Oct 2017, Marseille, France. pp.196, ⟨10.1111/jnc.13925⟩
Conference papers hal-02334376v1

Pinnatoxins: an emergent family of marine phycotoxins targeting nicotinic acetylcholine receptors with high affinity

Rómulo Aráoz , Denis Servent , Jordi Molgo , Bogdan Iorga , C. Fruchard-Gaillard , et al.
J. Barbier, E. Benoit, N. Gilles, D. Ladant, M.-F. Martin-Eauclaire, C. Mattéi, J. Molgó, M.R. Poppof & D. Servent. Toxins and Ion transfers, SFET Publications, pp.43-47, 2011, Collection Rencontres en Toxinologie, 1760-6004
Book sections hal-02334617v1
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A snake toxin as a theranostic agent for the type 2 vasopressin receptor

Laura Droctové , Manon Lancien , Vu Long Tran , Michaël Susset , Benoit Jego , et al.
Theranostics, 2020, 10 (25), pp.11580-11594. ⟨10.7150/thno.47485⟩
Journal articles hal-02960704v1

Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease

Justyna Ciolek , Helen Reinfrank , Loïc Quinton , Say Viengchareun , Enrico A. Stura , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (27), pp.7154-7159. ⟨10.1073/pnas.1620454114⟩
Journal articles hal-02050051v1
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Toxins and Ion transfers

Julien Barbier , Evelyne Benoit , Nicolas Gilles , Daniel Ladant , Marie-France Martin-Eauclaire , et al.
SFET Publications, Gif-sur-Yvette, France, pp.123, 2011
Books hal-00738632v1

A non-invasive method to appraise time-dependent effects of venom toxins on the mouse neuromuscular excitability in vivo

Tânia C. Gonçalves , Michel Partiseti , Denis Servent , Evelyne Benoit
Toxicon, 2018, 149, pp.104. ⟨10.1016/j.toxicon.2018.02.030⟩
Journal articles hal-02334359v1

Cyclic imine toxins: From shellfish poisoning to neuroscience: The case of acyl derivatives

Rómulo Aráoz , Philipp Hess , Franck Pélissier , Evelyne Benoit , Denis Servent , et al.
5th nAChR satellite symposium on « Nicotinic Acetylcholine Receptors as Therapeutic Targets: Emerging Frontiers in Basic Research & Clinical Science », Oct 2015, Chicago, United States. pp.622, ⟨10.1016/j.bcp.2015.08.007⟩
Conference papers hal-02334385v1

The marine phycotoxin gymnodimine targets muscular and neuronal nicotinic acetylcholine receptor subtypes with high affinity.

Riadh Kharrat , Denis Servent , Emmanuelle Girard , Gilles Ouanounou , Muriel Amar , et al.
Journal of Neurochemistry, 2008, 107 (4), pp.952-63. ⟨10.1111/j.1471-4159.2008.05677.x⟩
Journal articles hal-00316051v1

Pinnatoxins, an emergent class of marine toxins interacting with nAChRs. Pharmacological characterization, biodistribution and musculo-skeletal effect of these neurotoxic agents

Denis Servent , Sophie Creuzet , Carole Malgorn , Vincent Dive , Armen Zakarian , et al.
Toxicon, 2020, 177 (Suppl 1), pp.S3. ⟨10.1016/j.toxicon.2019.10.015⟩
Journal articles hal-02912939v1
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Gambierol Potently Increases Evoked Quantal Transmitter Release and Reverses Pre- and Post-Synaptic Blockade at Vertebrate Neuromuscular Junctions

Jordi Molgó , Sébastien Schlumberger , Makoto Sasaki , Haruhiko Fuwa , Carmen M. Louzao , et al.
Neuroscience, 2020, 439, pp.106-116. ⟨10.1016/j.neuroscience.2019.06.024⟩
Journal articles hal-02324830v1

Mambalgins, snake peptides against inflammatory and neuropathic pain through inhibition of ASIC channels

Anne Baron , Sylvie Diochot , Miguel Salinas , Abdelkrim Alloui , Dominique Douguet , et al.
SFET Société Française d'Etude des Toxines, Dec 2016, Paris, France. pp.93, ⟨10.1016/j.toxicon.2017.12.026⟩
Conference papers hal-02355724v1

Toxins: New Targets and New Functions

Jordi Molgó , Evelyne Benoit , Julien Barbier , Michel Popoff , Grazyna Faure , et al.
J. MOLGO, E. BENOIT, J. BARBIER, M.R. POPPOF, G. FAURE & D. SERVENT (Eds). Rencontres en Toxinologie « Toxins: New Targets and New Functions » organisées par la Société Française pour l'Etude des Toxines, Dec 2014, Paris, France. Toxicon, 116, Elsevier, 2016, Special issue of Toxicon, 0041-0101
Special issue hal-02334653v1
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Direct evidence for high affinity blockade of Nav1.6 channel subtype by huwentoxin-IV spider peptide, using multiscale functional approaches

Tânia C. Gonçalves , Rachid Boukaiba , Jordi Molgó , Muriel Amar , Michel Partiseti , et al.
Neuropharmacology, 2018, 133, pp.404-414. ⟨10.1016/j.neuropharm.2018.02.016⟩
Journal articles hal-01828943v1
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The Dinoflagellate Toxin 20-Methyl Spirolide-G Potently Blocks Skeletal Muscle and Neuronal Nicotinic Acetylcholine Receptors.

Aurélie Couesnon , Rómulo Aráoz , Bogdan I Iorga , Evelyne Benoit , Morgane Reynaud , et al.
Toxins, 2016, 8 (9), pp.249. ⟨10.3390/toxins8090249⟩
Journal articles hal-01443823v1

Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal α7 from Muscle α12βγδ nAChRs.

Yves Bourne , Gerlind Sulzenbacher , Zoran Radić , Rómulo Aráoz , Morgane Reynaud , et al.
Structure (London, England : 1993), 2015, 23 (6), pp.1106-15. ⟨10.1016/j.str.2015.04.009⟩
Journal articles hal-01178822v1

Functional determinants by which snake and cone snail toxins block the alpha 7 neuronal nicotinic acetylcholine receptors.

Denis Servent , Hung Lam Thanh , Stéphanie Antil , Daniel Bertrand , Pierre-Jean Corringer , et al.
Journal of Physiology - Paris, 1998, 92 (2), pp.107-11. ⟨10.1016/S0928-4257(98)80146-0⟩
Journal articles istex pasteur-01718432v1

Identification of a novel snake peptide toxin displaying high affinity and antagonist behaviour for the α(2) -adrenoceptors.

Céline Rouget , Loïc Quinton , Arhamatoulaye Maïga , Céline Gales , Geoffrey Masuyer , et al.
British Journal of Pharmacology, 2010, epub ahead of print. ⟨10.1111/j.1476-5381.2010.00966.x⟩
Journal articles hal-00528529v1

Influence of MT7 toxin on the oligomerization state of the M1 muscarinic receptor.

Catherine Marquer , Carole Fruchart-Gaillard , Gilles Mourier , Olivier Grandjean , Emmanuelle Girard , et al.
Biology of the Cell, 2010, 102 (7), pp.409-20. ⟨10.1042/BC20090171⟩
Journal articles hal-00856094v1
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Mambalgin-1 pain-relieving peptide locks the hinge between α4 and α5 helices to inhibit rat Acid-Sensing Ion Channel 1a

Miguel Salinas , Pascal Kessler , Dominique Douguet , Daad Sarraf , Nicolo Tonali , et al.
Neuropharmacology, 2021, 185, pp.108453. ⟨10.1016/j.neuropharm.2021.108453⟩
Journal articles hal-03115234v1

Efficient functional neutralization of lethal peptide toxins in vivo by oligonucleotides

Tarek Mohamed Abd El-Aziz , Corinne Ravelet , Jordi Molgó , Emmanuelle Fiore , Simon Pale , et al.
Scientific Reports, 2017, 7 (1), ⟨10.1038/s41598-017-07554-5⟩
Journal articles hal-01639599v1
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Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors

Jordi Molgó , P. Marchot , Rómulo Aráoz , Evelyne Benoit , Bogdan I Iorga , et al.
Journal of Neurochemistry, 2017, 142, pp.41 - 51. ⟨10.1111/jnc.13995⟩
Journal articles hal-01661784v1
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Prorocentrolide-A from Cultured Prorocentrum lima Dinoflagellates Collected in Japan Blocks Sub-Types of Nicotinic Acetylcholine Receptors

Muriel Amar , Rómulo Aráoz , Bogdan Iorga , Takeshi Yasumoto , Denis Servent , et al.
Toxins, 2018, 10 (3), pp.97. ⟨10.3390/toxins10030097⟩
Journal articles hal-01828952v1

Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition

Gilles Mourier , Miguel Salinas , Pascal Kessler , Enrico Stura , Mathieu Leblanc , et al.
Journal of Biological Chemistry, 2016, 291 (6), pp.2616-2629. ⟨10.1074/jbc.M115.702373⟩
Journal articles hal-02267121v1
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Mambalgins, Snake Peptides Against Inflammatory and Neuropathic Pain Through Inhibition of ASIC Channels

Anne Baron , Sylvie Diochot , Miguel Salinas , Abdelkrim Alloui , Dominique Douguet , et al.
Toxicon, 2018, 149, pp.93. ⟨10.1016/j.toxicon.2017.12.026⟩
Journal articles hal-02368770v1

A synthetic weak neurotoxin binds with low affinity to Torpedo and chicken alpha7 nicotinic acetylcholine receptors.

Siew Lay Poh , Gilles Mourier , Robert Thai , Arunmozhiarasi Armugam , Jordi Molgó , et al.
European Journal of Biochemistry, 2002, 269 (17), pp.4247-56. ⟨10.1046/j.1432-1033.2002.03113.x⟩
Journal articles hal-00193986v1

Toxins: From Threats to Benefits

Jordi Molgó , Evelyne Benoit , Julien Barbier , P. Marchot , Denis Servent
J. MOLGO, E. BENOIT, J. BARBIER, P. MARCHOT & D. SERVENT (Eds). Rencontres en Toxinologie « Toxins: From Threats to Benefits » organisées par la Société Française pour l'Etude des Toxines (2012), Dec 2012, Paris, France. Toxicon, 75, Elsevier, 2013, Special issue of Toxicon, 0041-0101
Special issue hal-02334645v1

The cyclic imine family of dinoflagellate toxins targeting nicotinic acetylcholine receptors

Jordi Molgó , Muriel Amar , Rómulo Aráoz , Evelyne Benoit , Bogdan Iorga , et al.
Toxicon, 2019, 158, pp.S22. ⟨10.1016/j.toxicon.2018.10.080⟩
Journal articles hal-02334357v1