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Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology
Sophie Ayciriex
,
Marie-Anne Burlot
,
Jérome Braudeau
,
Kristin Michaelsen-Preusse
,
Brigitte Potier
,
et al.
Journal articles
hal-01779042v1
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Complete Correction of Brain and Spinal Cord Pathology in Metachromatic Leukodystrophy Mice
Emilie Audouard
,
Valentin Oger
,
Béatrix Meha
,
Nathalie Cartier
,
Caroline Sevin
,
et al.
Journal articles
hal-03254121v1
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The challenge of gene therapy for neurological diseases: strategies and tools to achieve efficient delivery to the central nervous system
Timothée de Saint Denis
,
Françoise Piguet
,
Emilie Audouard
,
Kevin Beccaria
,
Arthur André
,
et al.
Journal articles
hal-03265982v1
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βAPP Processing Drives Gradual Tau Pathology in an Age-Dependent Amyloid Rat Model of Alzheimer’s Disease
Mickael Audrain
,
Benoit Souchet
,
Sandro Alves
,
Romain Fol
,
Arthur Viodé
,
et al.
Journal articles
hal-02324980v1
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CYP46A1 inhibition, brain cholesterol accumulation and neurodegeneration pave the way for Alzheimer’s disease
Sophie Ayciriex
,
Fathia Djelti
,
Jérome Braudeau
,
Eloise Hudry
,
Marc Dhenain
,
et al.
Journal articles
hal-01779044v1
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Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia
Marina Cavazzana-Calvo
,
Emmanuel Payen
,
Olivier Negre
,
Gary Wang
,
Kathleen Hehir
,
et al.
Journal articles
cea-00905288v1
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Intracerebral gene therapy in children with metachromatic leukodystrophy: Results of a phase I/II trial
Caroline Sevin
,
Thomas Roujeau
,
Nathalie Cartier
,
Thomas Baugnon
,
Catherine Adamsbaum
,
et al.
Conference papers
hal-02737676v1
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CYP46A1, the rate-limiting enzyme for cholesterol degradation, is neuroprotective in Huntington’s disease
Lydie Boussicault
,
Sandro Alves
,
Antonin Lamazière
,
Anabelle Planques
,
Nicolas Heck
,
et al.
Journal articles
hal-01299208v1
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Inhibition of DYRK1A proteolysis modifies its kinase specificity and rescues Alzheimer phenotype in APP/PS1 mice
Benoit Souchet
,
Mickael Audrain
,
Jean Marie Billard
,
Julien Dairou
,
Romain Fol
,
et al.
Journal articles
hal-02324924v1
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Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins
Sandro Alves
,
Thibaut Marais
,
Maria-Grazia Biferi
,
Denis Furling
,
Martina Marinello
,
et al.
Journal articles
hal-01371536v1
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Neuronal Cholesterol Accumulation Induced by Cyp46a1 Down-Regulation in Mouse Hippocampus Disrupts Brain Lipid Homeostasis
Sophie Ayciriex
,
Fathia Djelti
,
Sandro Alves
,
Anne Regazzetti
,
Mathieu Gaudin
,
et al.
Journal articles
hal-03220550v1
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Hematopoietic stem cell Gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy
Nathalie Cartier
,
Salima Hacein-Bey-Abina
,
Cynthia C. Bartholomae
,
Gabor Veres
,
Manfred Schmidt
,
et al.
Journal articles
cea-00817492v1
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Alzheimer's disease-like APP processing in wild-type mice identifies synaptic defects as initial steps of disease progression.
Mickael Audrain
,
Romain Fol
,
Patrick Dutar
,
Brigitte Potier
,
Jean-Marie Billard
,
et al.
Journal articles
inserm-01322473v1
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Intra-CSF AAV9 and AAVrh10 Administration in Nonhuman Primates: Promising Routes and Vectors for Which Neurological Diseases?
Karim Bey
,
Johan Deniaud
,
Laurence Dubreil
,
Béatrice Joussemet
,
Joseph Cristini
,
et al.
Journal articles
hal-02561949v1
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Reply: Beneficial effect of interleukin-2-based immunomodulation in Alzheimer-like pathology
Sandro Alves
,
Guillaume Churlaud
,
David Klatzmann
,
Nathalie Cartier
Journal articles
inserm-01617417v1
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Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer’s disease mice
Sandro Alves
,
Guillaume Churlaud
,
Mickael Audrain
,
Kristin Michaelsen-Preusse
,
Romain Fol
,
et al.
Journal articles
hal-01430973v1
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Real-Time Monitoring of Exosome Enveloped-AAV Spreading by Endomicroscopy Approach: A New Tool for Gene Delivery in the Brain
Nicola Salvatore Orefice
,
Benoît Souchet
,
Jérôme Braudeau
,
Sandro Alves
,
Françoise Piguet
,
et al.
Journal articles
cea-02997523v1
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