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authFullName_s : Jean-Christophe Cintrat

Retrograde transport is not required for cytosolic translocation of the B-subunit of Shiga toxin

Maria Daniela Garcia-Castillo , Thi Tran , Alexandre Bobard , Henri-François Renard , Stefan Rathjen , et al.
Journal of Cell Science, 2015, 128 (13), pp.2373 - 2387. ⟨10.1242/jcs.169383⟩
Journal articles pasteur-01899449v1
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Shiga Toxin Uptake and Sequestration in Extracellular Vesicles Is Mediated by Its B-Subunit

Annie Willysson , Anne-Lie Ståhl , Daniel Gillet , Julien Barbier , Jean-Christophe Cintrat , et al.
Toxins, 2020, 12 (7), ⟨10.3390/toxins12070449⟩
Journal articles cea-03023143v1

Functional dissection of the retrograde Shiga toxin trafficking inhibitor Retro-2

Alison Forrester , Stefan Rathjen , Maria Daniela Garcia-Castillo , Collin Bachert , Audrey Couhert , et al.
Nature Chemical Biology, 2020, 16 (3), pp.327-336. ⟨10.1038/s41589-020-0474-4⟩
Journal articles hal-04003230v1

Experimental observation of double-walled peptide nanotubes and monodispersity modeling of the number of walls.

Frédéric Gobeaux , Nicolas Fay , Christophe Tarabout , Florian Meneau , Cristelle Meriadec , et al.
Langmuir, 2013, 29 (8), pp.2739-45. ⟨10.1021/la304862f⟩
Journal articles hal-00814021v1
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Regioselective Halogenation of 1,4-Benzodiazepinones via CH Activation

Hajer Abdelkafi , Jean-Christophe Cintrat
Scientific Reports, 2015, 5 (1), ⟨10.1038/srep12131⟩
Journal articles cea-02075732v1

Nanotubes biomimétiques : synthèse, caractérisation et incroporation en photonique intégrée sur organiques

Christophe Tarabout , Nicolas Fay , Daphné Duval , Emilie Pouget , Etienne Gaviot , et al.
4èmes Journées Biologie-Biophysique, Jun 2009, Baden-Berder, France
Conference papers hal-00652399v1
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The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides

Xin Ming , Kyle Carver , Michael Fisher , Romain Noël , Jean-Christophe Cintrat , et al.
Nucleic Acids Research, 2013, 41 (6), pp.3673-3687. ⟨10.1093/nar/gkt066⟩
Journal articles cea-02432369v1

Footprinting of protein interactions by tritium labeling

Guillaume Mousseau , Quentin Raffy , Olivier Thomas , Morgane Agez , Robert Thai , et al.
British Journal of Pharmacology, 2010, 159 (2), pp.316-325. ⟨10.1021/bi100031a⟩
Journal articles cea-02000386v1

Structure–Activity Relationship Studies of Retro-1 Analogues against Shiga Toxin

Hajer Abdelkafi , Aurélien Michau , Valérie Pons , Flora Ngadjeua , Alexandra Clerget , et al.
Journal of Medicinal Chemistry, 2020, 63 (15), pp.8114-8133. ⟨10.1021/acs.jmedchem.0c00298⟩
Journal articles hal-03320788v1

Regulation of endo-lysosomal pathway and autophagic flux by broad-spectrum anti-pathogen inhibitor ABMA

Yu Wu , Claire Boulogne , Stefan Carle , Maria Podinovskaia , Holger Barth , et al.
FEBS Journal, 2020, ⟨10.1111/febs.15201⟩
Journal articles hal-02445466v1

Measurement of Long-Range Interatomic Distances by Solid-State Tritium-NMR Spectroscopy

Alexander K. L. Yuen , Olivier Lafon , Thibault Charpentier , Myriam Roy , Francine Brunet , et al.
Journal of the American Chemical Society, 2010, 132, pp.1734
Journal articles hal-00460777v1

Control of peptide nanotube diameter by chemical modifications of an aromatic residue involved in a single close contact.

Christophe Tarabout , Stéphane Roux , Frédéric Gobeaux , Nicolas Fay , Emilie Pouget , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (19), pp.7679-84. ⟨10.1073/pnas.1017343108⟩
Journal articles inserm-00716817v1
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Broad spectrum compounds targeting early stages of rabies virus (RABV) infection

Sabrina Kali , Corinne Jallet , Saliha Azebi , Thomas Cokelaer , Juliana Pipoli da Fonseca , et al.
Antiviral Research, 2021, 188, pp.105016. ⟨10.1016/j.antiviral.2021.105016⟩
Journal articles pasteur-03281530v1
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Revisiting Old Ionophore Lasalocid as a Novel Inhibitor of Multiple Toxins

Nassim Mahtal , Yu Wu , Jean-Christophe Cintrat , Julien Barbier , Emmanuel Lemichez , et al.
Toxins, 2020, 12 (1), pp.26. ⟨10.3390/toxins12010026⟩
Journal articles pasteur-02448862v1
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Antiviral Effects of ABMA against Herpes Simplex Virus Type 2 In Vitro and In Vivo

Wenwen Dai , Yu Wu , Jinpeng Bi , Shuai Wang , Fang Li , et al.
Viruses, 2018, 10 (3), pp.119. ⟨10.3390/v10030119⟩
Journal articles cea-02432376v1
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Identification of small molecules inhibiting cardiomyocyte necrosis and apoptosis by autophagy induction and metabolism reprogramming

Dawei Liu , Félix Peyre , Yahir Alberto Loissell-Baltazar , Delphine Courilleau , Sandra Lacas-Gervais , et al.
Cells, 2022, 11 (3), pp.474. ⟨10.3390/cells11030474⟩
Journal articles hal-03804118v1

Structural role of counterions adsorbed on self-assembled peptide nanotubes.

Frédéric Gobeaux , Nicolas Fay , Christophe Tarabout , Cristelle Meriadec , Florian Meneau , et al.
Journal of the American Chemical Society, 2012, 134 (1), pp.723-33. ⟨10.1021/ja210299g⟩
Journal articles hal-00910874v1
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C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus

Yu Wu , Nassim Mahtal , Eléa Paillares , Léa Swistak , Sara Sagadiev , et al.
iScience, 2022, 25 (7), pp.104537. ⟨10.1016/j.isci.2022.104537⟩
Journal articles inserm-03741921v1

Chemical inhibitors of monogalactosyldiacylglycerol synthases in Arabidopsis thaliana.

Cyrille y Botté , Michael Deligny , Aymeric Roccia , Anne-Laure Bonneau , Nadia Saïdani , et al.
Nature Chemical Biology, 2011, 7 (11), pp.834-842. ⟨10.1038/nchembio.658⟩
Journal articles hal-00636525v1
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2-Guanidino-quinazoline promotes the readthrough of nonsense mutations underlying human genetic diseases

Laure Bidou , Olivier Bugaud , Goulven Merer , Matthieu Coupet , Isabelle Hatin , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (35), ⟨10.1073/pnas.2122004119/-/DCSupplemental⟩
Journal articles hal-03783009v1

Functional dissection of the retrograde Shiga toxin trafficking inhibitor Retro-2

Alison Forrester , Stefan Rathjen , Maria Daniela Garcia-Castillo , Collin Bachert , Audrey Couhert , et al.
Nature Chemical Biology, 2020, 16 (3), pp.327-336. ⟨10.1038/s41589-020-0474-4⟩
Journal articles hal-03321166v1

Tritium solid-state NMR: Towards long-range distance measurements in biological complexes

Olivier Lafon , Thibault Charpentier , Dimitris Sakellariou , Patrick Berthault , Alexander Yuen , et al.
5th Alpine Conference on Solid-State NMR, Sep 2007, Chamonix, France
Conference papers hal-00173704v1

Screening of a Drug Library Identifies Inhibitors of Cell Intoxication by CNF1

Nassim Mahtal , Clémence Brewee , Sylvain Pichard , Orane Visvikis , Jean-Christophe Cintrat , et al.
ChemMedChem, 2018, 13 (7), pp.754-761. ⟨10.1002/cmdc.201700631⟩
Journal articles pasteur-02448858v1

Discovery of compounds blocking the proliferation of Toxoplasma gondii and Plasmodium falciparum in a chemical space based on piperidinyl-benzimidazolidinone analogs.

Nadia Saïdani , Cyrille y Botté , Michael Deligny , Anne-Laure Bonneau , Janette Reader , et al.
Antimicrobial Agents and Chemotherapy, 2014, 58 (5), pp.2586-2597. ⟨10.1128/AAC.01445-13⟩
Journal articles hal-00966432v1

Glucocorticoids delay RAF-induced senescence promoted by EGR1

Cyril Carvalho , Valentin L'Hôte , Régis Courbeyrette , Gueorgui Kratassiouk , Guillaume Pinna , et al.
Journal of Cell Science, 2019, 132 (16), pp.jcs230748. ⟨10.1242/jcs.230748⟩
Journal articles hal-02330078v1

Flexizyme-aminoacylated shortened tRNAs demonstrate that only the aminoacylated acceptor arms of the two tRNA substrates are required for cyclodipeptide synthase activity

Nicolas Canu , Carine Tellier , Morgan Babin , Robert Thai , Inès Ajel , et al.
Nucleic Acids Research, 2020, 48 (20), ⟨10.1093/nar/gkaa903⟩
Journal articles hal-02978046v1
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ABMA, a small molecule that inhibits intracellular toxins and pathogens by interfering with late endosomal compartments

Yu Wu , Valérie Pons , Amélie Goudet , Laetitia Panigai , Annette Fischer , et al.
Scientific Reports, 2017, 7 (1), pp.15567. ⟨10.1038/s41598-017-15466-7⟩
Journal articles pasteur-01675662v1
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Directing peptide crystallization through curvature control of nanotubes ‡

Frédéric Gobeaux , Christophe Tarabout , Nicolas Fay , Cristelle Mériadec , Melinda Ligeti , et al.
Journal of Peptide Science, 2014, 20 (7), pp.508-516. ⟨10.1002/psc.2647⟩
Journal articles cea-01201911v1
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NMR Characterization of the Influence of Zinc(II) Ions on the Structural and Dynamic Behavior of the New Delhi Metallo-β-Lactamase-1 and on the Binding with Flavonols as Inhibitors

Gwladys Rivière , Saoussen Oueslati , Maud Gayral , Jean-Bernard Créchet , Naïma Nhiri , et al.
ACS Omega, 2020, 5 (18), pp.10466-10480. ⟨10.1021/acsomega.0c00590⟩
Journal articles hal-02604220v1

DABMA: A Derivative of ABMA with Improved Broad-Spectrum Inhibitory Activity of Toxins and Viruses

Yu Wu , Valérie Pons , Romain Noël , Sabrina Kali , Olena Shtanko , et al.
ACS Medicinal Chemistry Letters, 2019, 10 (8), pp.1140-1147. ⟨10.1021/acsmedchemlett.9b00155⟩
Journal articles pasteur-02453943v1