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[18F]-FMISO PET study of hypoxia in gliomas before surgery: correlation with molecular markers of hypoxia and angiogenesis.

L Bekaert , S Valable , E Lechapt-Zalcman , K Ponte , S Collet , et al.
European Journal of Nuclear Medicine and Molecular Imaging, 2017, 44 (8), pp.1383-1392. ⟨10.1007/s00259-017-3677-5⟩
Journal articles hal-01575007v1

FMISO-PET-derived brain oxygen tension maps: application to glioblastoma and less aggressive gliomas

Ararat Chakhoyan , Jean-Sébastien Guillamo , Solène Collet , François Kauffmann , Nicolas Delcroix , et al.
Scientific Reports, 2017, 7 (1), ⟨10.1038/s41598-017-08646-y⟩
Journal articles hal-02043459v1

Dihydroquinoline Carbamate Derivatives as "Bio-oxidizable" Prodrugs for Brain Delivery of Acetylcholinesterase Inhibitors: [¹¹C] Radiosynthesis and Biological Evaluation

Pierre Bohn , F. Gourand , Cyril Papamicaël , M. Ibazizène , M Dhilly , et al.
ACS Chemical Neuroscience, 2015, 6 (5), pp.737-744. ⟨10.1021/cn5003539⟩
Journal articles hal-01578046v1
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Evaluation of Specific Binding of [11C]RTI-97 to KOR by Autoradiog-raphy and PET Imaging in Rat

Fabien Fillesoye , Méziane Ibazizene , Nicolas Marie , Florence Noble , Cécile Perrio
ACS Medicinal Chemistry Letters, 2021, 12 (11), pp.1739-1744. ⟨10.1021/acsmedchemlett.1c00369⟩
Journal articles hal-03381883v1

Imaging of brain oxygenation with magnetic resonance imaging : A validation with positron emission tomography in the healthy and tumoural brain.

S Valable , A Corroyer-Dulmont , A Chakhoyan , L Durand , J Toutain , et al.
Journal of Cerebral Blood Flow and Metabolism, 2017, 37 (7), pp.2584-2597. ⟨10.1177/0271678X16671965⟩
Journal articles hal-01575065v1

Simultaneous tritium labelling of two potent 5-HT4 ligands

Franck Sobrio , Stéphane Lemaitre , Antoine Hinsberger , Louisa Barre , Bernard Rousseau , et al.
European Journal of Medicinal Chemistry, 2010, 45 (3), pp.1263-1265
Journal articles hal-02045952v1

18 F-Fludarabine PET for Lymphoma Imaging: First-in-Humans Study on DLBCL and CLL Patients

Sylvain Chantepie , Narinée Hovhannisyan , Stéphane Guillouet , Jean-Pierre J.-P. Pelage , Méziane Ibazizene , et al.
Journal of Nuclear Medicine, 2018, 59 (9), pp.1380-1385. ⟨10.2967/jnumed.117.206920⟩
Journal articles hal-02006592v1

2-[18F]Fludarabine, a Novel Positron Emission Tomography (PET) Tracer for Imaging Lymphoma: a Micro-PET Study in Murine Models

Martine Dhilly , Stéphane Guillouet , Delphine Patin , Fabien Fillesoye , Ahmed Abbas , et al.
Molecular Imaging and Biology, 2014, 16 (1), pp.118 - 126. ⟨10.1007/s11307-013-0659-2⟩
Journal articles hal-01599730v1
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Simultaneous mapping of vasculature, hypoxia and proliferation using DSC-MRI, 18F-FMISO PET, and 18F-FLT PET in relation to contrast enhancement in newly diagnosed glioblastoma

Solène Collet , Jean Sébastien Guillamo , David Hassanein Berro , Ararat Chakhoyan , Jean-Marc Constans , et al.
Journal of Nuclear Medicine, 2021, 62 (10), pp.1349-1356. ⟨10.2967/jnumed.120.249524⟩
Journal articles hal-03123047v1

N-[18F]-FluoropropylJDTic for κ-opioid receptor PET imaging : Radiosynthesis, pre-clinical evaluation, and metabolic investigation in comparison with parent JDTic.

S Schmitt , J Delamare , O Tirel , F Fillesoye , M Dhilly , et al.
Nuclear Medicine and Biology, 2017, 44, pp.50-61. ⟨10.1016/j.nucmedbio.2016.09.005⟩
Journal articles hal-01575523v1

Synthesis and in vitro characterization of trans- and cis-[18F]-4-methylbenzyl 4-[(pyrimidin-2-ylamino)methyl]-3-fluoropiperidine-1-carboxylates as new potential PET radiotracer candidates for the NR2B subtype N-methyl-d-aspartate receptor

Radouane Koudih , Gwénaëlle Gilbert , Martine Dhilly , Ahmed Abbas , Louisa Barre , et al.
European Journal of Medicinal Chemistry, 2012, 53, pp.408 - 415. ⟨10.1016/j.ejmech.2012.04.011⟩
Journal articles hal-01853609v1
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[18F]Fludarabine-PET in a murine model of multiple myeloma

N Hovhannisyan , M Dhilly , M Fidalgo , F Fillesoye , S Guillouet , et al.
PLoS ONE, 2017, 12 (5), pp.e0177125. ⟨10.1371/journal.pone.0177125⟩
Journal articles hal-01575068v1

[ 18 F]Fludarabine-PET as a promising tool for differentiating CNS lymphoma and glioblastoma: Comparative analysis with [ 18 F]FDG in human xenograft models

Narinée Hovhannisyan , Fabien Fillesoye , Stéphane Guillouet , Méziane Ibazizene , Jérôme Toutain , et al.
Theranostics, 2018, 8 (16), pp.4563-4573. ⟨10.7150/thno.26754⟩
Journal articles hal-02006576v1

Novel fluoroalkyl derivatives of selective kappa opioid receptor antagonist JDTic: Design, synthesis, pharmacology and molecular modeling studies.

S Schmitt , N Colloc'H , C Perrio
European Journal of Medicinal Chemistry, 2015, 90, pp.742-50. ⟨10.1016/j.ejmech.2014.12.016⟩
Journal articles hal-01576209v1

StO2-MRI sensitively images the ischemic brain: a comparison to MRI perfusion/diffusion mismatch and [18F]-FMISO-PET

S Valable , J Toutain , D Divoux , L Chazalviel , A Corroyer-Dulmont , et al.
28th International Symposium on Cerebral Blood Flow, Metabolism and Function & 13th International Conference on Quantification of Brain Function with PET, Apr 2017, Berlin, Germany. Journal of Cerebral Blood Flow and Metabolism, 37, S1, pp.219
Conference poster hal-02265365v1

Gallium-68 Complexes Conjugated to Pittsburgh Compound B: Radiolabeling and Biological Evaluation

D Cressier , M Dhilly , Tt Cao Pham , F Fillesoye , F Gourand , et al.
Molecular Imaging and Biology, 2016, 18 (3), pp.334-43. ⟨10.1007/s11307-015-0906-9⟩
Journal articles hal-01575680v1

Feasibility of, and critical paths for mycophenolate mofetil Bayesian dose adjustment: Pharmacological re-appraisal of a concentration-controlled versus fixed-dose trial in renal transplant recipients

Aurelie Prémaud , Annick Rousseau , Yannick Le Meur , Nicolas Venisse , Cecile Loichot-Roselmac , et al.
Pharmacological Research, 2010, 61 (2), pp.167 - 174. ⟨10.1016/j.phrs.2009.09.006⟩
Journal articles hal-03134625v1

[11C]MADAM used as a model for understanding the radiometabolism of diphenyl sulfide radioligands for positron emission tomography (PET)

F Gourand , N Amini , Z Jia , S Stone-Elander , D Guilloteau , et al.
PLoS ONE, 2015, 10 ((9)), pp.e0137160. ⟨10.1371/journal.pone.0137160⟩
Journal articles hal-01587383v1
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New developments in redox chemical delivery systems by means of 1,4-dihydroquinoline-based targetor: Application to galantamine delivery to the brain

Mihaela-Liliana Tîntas , Lénaïg Foucout , Sylvain Petit , Sylvain Oudeyer , Fabienne Gourand , et al.
European Journal of Medicinal Chemistry, 2014, 81, pp.218 - 226. ⟨10.1016/j.ejmech.2014.05.022⟩
Journal articles hal-03856118v1
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Hypoxia Imaging and Adaptive Radiotherapy: A State-of-the-Art Approach in the Management of Glioma

Michael Gérard , Aurélien Corroyer-Dulmont , Paul Lesueur , Solène Collet , Michel Chérel , et al.
Frontiers in Medicine, 2019, 6:117, ⟨10.3389/fmed.2019.00117⟩
Journal articles hal-02153761v1

Nucleophilic radiofluorination at room temperature via aziridinium intermediates

M Médoc , F Sobrio
Journal of Organic Chemistry, 2015, 80 (20), pp.10086-97. ⟨10.1021/acs.joc.5b01714⟩
Journal articles hal-01578088v1

Radiolabelling of 1,4-disubstituted 3-[18F]fluoropiperidines and its application to new radiotracers for NR2B NMDA receptor visualization

Radouane Koudih , Gwénaëlle Gilbert , Martine Dhilly , Ahmed Abbas , Louisa Barre , et al.
Organic & Biomolecular Chemistry, 2012, 10 (42), ⟨10.1039/c2ob26378e⟩
Journal articles hal-01853954v1

ZAP-70 intron1 DNA methylation status: Determination by pyrosequencing in B chronic lymphocytic leukemia

Sylvain Chantepie , Dominique Vaur , Christoph Grunau , Véronique Salaün , Mélanie Briand , et al.
Leukemia Research, 2010, 34 (6), pp.800-808. ⟨10.1016/j.leukres.2009.10.018⟩
Journal articles istex hal-02358614v1

PET imaging with [18F]AV-45 in an APP/PS1-21 murine model of amyloid plaque deposition

Géraldine Poisnel , Martine Dhilly , Olivier Moustié , Jérôme Delamare , Ahmed Abbas , et al.
Neurobiology of Aging, 2012, 33 (11), pp.2561 - 2571. ⟨10.1016/j.neurobiolaging.2011.12.024⟩
Journal articles hal-01853953v1

Argon prevents the development of locomotor sensitization to amphetamine and amphetamine-induced changes in mu opioid receptor in the nucleus accumbens

Hélène David , Martine Dhilly , Géraldine Poisnel , Mickael Degoulet , Cédric Meckler , et al.
Medical Gas Research, 2014, 4 (1), ⟨10.1186/s13618-014-0021-z⟩
Journal articles hal-01629139v1

Pd(0)-Catalyzed Direct C-H Functionalization of 2-H-4-Benzylidene Imidazolones: Friendly and Large-Scale Access to GFP and Kaede Protein Fluorophores

Mickaël Muselli , Christine Baudequin , Cécile Perrio , Christophe Hoarau , Laurent Bischoff
Chemistry - A European Journal, 2016, 22 (16), pp.5520-5524. ⟨10.1002/chem.201600602⟩
Journal articles istex hal-01575627v1

A radiometabolite study of the serotonin transporter PET radioligand [11C]MADAM

F. Gourand , P. Emond , J.P. Bergström , A. Takano , B. Gulyás , et al.
Nuclear Medicine and Biology, 2014, 41 (6), pp.501 - 506. ⟨10.1016/j.nucmedbio.2014.03.022⟩
Journal articles hal-01626325v1

[ 18 F]-Fluoride capture and release: azeotropic drying free nucleophilic aromatic radiofluorination assisted by a phosphonium borane

Cécile Perrio , Sébastien Schmitt , Daniel Pla , François Gabbaï , Kantapat Chansaenpak , et al.
Chemical Communications, 2017, 53 (2), pp.340-343. ⟨10.1039/C6CC05168E⟩
Journal articles hal-02364262v1

In vivo evaluation of radiofluorinated caspases-3/7 inhibitors as radiotracers for apoptosis imaging and comparison with [18F]-ML-10 in a stroke model in the rat

M Médoc , M Dhilly , L Matesic , J Toutain , Am Krause-Heuer , et al.
Molecular Imaging and Biology, 2016, 18, pp.117-128. ⟨10.1007/s11307-015-0865-1⟩
Journal articles hal-01538309v1

Confocal Microscopy Imaging of NR2B-Containing NMDA Receptors Based on Fluorescent Ifenprodil-Like Conjugates

Patrice Marchand , Javier Becerril-Ortega , Laetitia Mony , Cédric Bouteiller , Pierre Paoletti , et al.
Bioconjugate Chemistry, 2011, 23 (1), pp.21 - 26. ⟨10.1021/bc100571g⟩
Journal articles hal-01853389v1