Soil pollution in the European Union (EU) is poorly quantified, because of several years of reduced attention and limited funding on soil research and monitoring. Moreover, issues such as different monitoring methodologies within Member States (MS), and quantification methods focused on pseudototal rather than the available fraction of pollutants, has been limiting our understanding of risk under soil pollution. Despite that, thanks to efforts from the scientific community, it was possible to achieve some progress, which is by far insufficient for the problem at hand. In the anticipation of future policy demands and towards a common strategy for tackling soil pollution in the EU, it seemed relevant to describe the limited knowledge and main uncertainties. Such analysis should provide evidence for the development of efficient policies, as well as updating current ones to better tackle the interdisciplinary of soil. This perspective provides our view on current knowledge on soil pollution at EU scale, by compiling the most updated assessments made at EU scale, identifying soil pollution drivers, impacts on health and the environment, and evaluating current state of knowledge. Allowing us to infer about current level of uncertainties and knowledge gaps and identify solutions through future research and policies. Our suggestions are in line with an increasing investment on research and innovation, but also more frequent updates of current legislation already tackling pollution and welcoming the new proposal for a Soil Monitoring Law as an important driver for soil knowledge development and implementation of a European monitoring system.