Carbon isotope labeling of carbamates by late-stage [$^{11}C$], [$^{13}C$] and [$^{14}C$] carbon dioxide incorporation
Résumé
A general procedure for the late-stage[$^{11}C$], [$^{13}C$] and [$^{14}C$] carbon isotope labeling of cyclic carbamates is reported. This protocol allows the incorporation of carbon dioxide, the primary source of carbon-14 and carbon-11 radioisotopes, in a direct, cost-effective and sustainable manner. A disconnection/reconnection strategy, involving ring opening/isotopic closure, was also implemented.
| Origine | Fichiers produits par l'(les) auteur(s) |
|---|
Loading...