Heritability of surface area and cortical thickness: a comparison between the Human Connectome Project and the UK Biobank dataset - CEA - Commissariat à l’énergie atomique et aux énergies alternatives Access content directly
Conference Papers Year : 2019

Heritability of surface area and cortical thickness: a comparison between the Human Connectome Project and the UK Biobank dataset

Abstract

Heritability of the regional thickness/surface in human cortex is established. Yet the estimates vary substantially depending on cohorts or the information they are derived from: pedigree or genotyping. Here we present three heritability studies of the cortex phenotype in two cohorts showing: i) both pedigree and genotyping or ii) genotyping only. We obtained clearly correlated heritability values between studies with a shift appearing between cohorts. Spatial pattern of heritability remains highly consistent across cohorts
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Dates and versions

cea-02016831 , version 1 (12-02-2019)

Identifiers

  • HAL Id : cea-02016831 , version 1

Cite

Yann Le Guen, Slim Karkar, Antoine Grigis, Cathy Philippe, Jean-François Mangin, et al.. Heritability of surface area and cortical thickness: a comparison between the Human Connectome Project and the UK Biobank dataset. ISBI 2019 - Proceedings of the IEEE International Symposium on Biomedical Imaging, 2019, Venice, Italy. ⟨cea-02016831⟩
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