%0 Journal Article %T Convergent genomic signatures of domestication in sheep and goats %+ Laboratoire d'Ecologie Alpine (LECA ) %+ School of Biosciences [Cardiff] %+ European Bioinformatics Institute [Hinxton] (EMBL-EBI) %+ Génétique Physiologie et Systèmes d'Elevage (GenPhySE ) %+ Section for GeoGenetics %+ PTP Science Park %+ Institute of Zootechnics [Piacenza] %+ Department of Environmental Sciences [Tarbiat] %+ Genoscope - Centre national de séquençage [Evry] (GENOSCOPE) %+ Institut de Biologie François JACOB (JACOB) %+ Laboratory of Geographical Information Systems (LASIG), School of Architecture, Civil and Environmental Engineering (ENAC) %+ Research Center on Biodiversity and Ancient DNA [Piacenza] (BioDNA) %+ Environmental Sciences Department [Gorgan] %+ Génomique métabolique (UMR 8030) %+ CSIRO Agriculture Flagship %+ Institut national de la recherche agronomique [Maroc] (INRA Maroc) %A Alberto, Florian %A Boyer, Frédéric %A Orozco-Terwengel, Pablo %A Streeter, Ian %A Servin, Bertrand %A de Villemereuil, Pierre %A Benjelloun, Badr %A Librado, Pablo %A Biscarini, Filippo %A Colli, Licia %A Barbato, Mario %A Zamani, Wahid %A Alberti, Adriana, A. %A Engelen, Stefan %A Stella, Alessandra %A Joost, Stéphane %A Ajmone-Marsan, Paolo %A Negrini, Riccardo %A Orlando, Ludovic %A Rezaei, Hamid Reza %A Naderi, Saeid %A Clarke, Laura %A Flicek, Paul %A Wincker, Patrick %A Coissac, Eric %A Kijas, James %A Tosser-Klopp, Gwenola %A Chikhi, Abdelkader %A Bruford, Michael %A Taberlet, Pierre %A Pompanon, François %Z FACCE ERA-NET Plus project CLIMGEN ANR-14-JFAC-0002-01 / LabEx OSUG (Investissements d'avenir) ANR10LABX56 / Wellcome Trust WT108749/Z/15/Z %< avec comité de lecture %@ 2041-1723 %J Nature Communications %I Nature Publishing Group %V 9 %N 1 %P 813 %8 2018-12 %D 2018 %R 10.1038/s41467-018-03206-y %M 29511174 %K dna-sequencing data %K population history %K analysis toolkit %K selection %K gene %K discovery %K reveals %K association %K animal domestication %K evolution %Z Life Sciences [q-bio] %Z Life Sciences [q-bio]/Genetics/Animal geneticsJournal articles %X The evolutionary basis of domestication has been a longstanding question and its genetic architecture is becoming more tractable as more domestic species become genome-enabled. Before becoming established worldwide, sheep and goats were domesticated in the fertile crescent 10,500 years before present (YBP) where their wild relatives remain. Here we sequence the genomes of wild Asiatic mouflon and Bezoar ibex in the sheep and goat domestication center and compare their genomes with that of domestics from local, traditional, and improved breeds. Among the genomic regions carrying selective sweeps differentiating domestic breeds from wild populations, which are associated among others to genes involved in nervous system, immunity and productivity traits, 20 are common to Capra and Ovis. The patterns of selection vary between species, suggesting that while common targets of selection related to domestication and improvement exist, different solutions have arisen to achieve similar phenotypic end-points within these closely related livestock species. %G English %2 https://cea.hal.science/cea-01875703/document %2 https://cea.hal.science/cea-01875703/file/2018_Alberto_Nature_Communications_1.pdf %L cea-01875703 %U https://cea.hal.science/cea-01875703 %~ CEA %~ UNIV-SAVOIE %~ UGA %~ CNRS %~ UNIV-EVRY %~ ENSA-TOULOUSE %~ INRA %~ OSUG %~ LECA %~ OPENAIRE %~ CEA-UPSAY %~ GENOMIQUE-METABOLIQUE %~ UNIV-PARIS-SACLAY %~ AGREENIUM %~ UNIV-EVRY-SACLAY %~ CEA-UPSAY-SACLAY %~ JACOB %~ CEA-DRF %~ GENOSCOPE %~ INRAE %~ TEST-HALCNRS %~ UGA-COMUE %~ USMB-COMUE %~ GENETIQUE_ANIMALE %~ ANR %~ GENPHYSE %~ GS-BIOSPHERA %~ INRAEOCCITANIETOULOUSE %~ TOULOUSE-INP %~ UT3-INP %~ UT3-TOULOUSEINP %~ TEST3-HALCNRS %~ TEST4-HALCNRS %~ ENVT %~ TEST5-HALCNRS