Biomimetic diamond MEMS sensors based on odorant-binding proteins: Sensors validation through an autonomous electronic system
Résumé
Odorant binding proteins (OBPs) have been considered one of the best candidates for conceiving a biosensor to detect biochemical molecules and for odor sensor applications. In the same way, MEMS sensors for chemical and biological applications proved to be a good option for applications requiring high sensitivity. In this context, micro-cantilever sensor is one of the most promising micromechanical sensor.
In this paper a grafting method, compatible with MEMS technology, was used for grafting porcine OBPs on polycrystalline diamond cantilevers. These sensors have been tested, for the first time, in combination with an autonomous dedicated electronic system developed to automatically detect sensors response signals. Electronic detection of binding 2-isobutyl-3-methoxypyrazine (IBMP) to OBP was demonstrated.
Mots clés
Biomimetics
Diamond
Bins
Grafting (chemical)
Nanocantilevers
MEMS
Odors
Proteins
Sensor arrays
Electronic nose
Polycrystalline diamonds
Signal detection
Sensor Array
Sensor read-out
Diamond micro-cantilever
Index Terms-Odorant Binding Proteins
Odorant-binding proteins
Autonomous electronics
Biochemical molecules
Chemical and biologicals
Micro cantilever sensors
Micro-cantilevers
Micromechanical sensors
Origine | Fichiers produits par l'(les) auteur(s) |
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